![]() The different pricing structures are as follows: There are three different membership levels, with increasing benefits as the price goes up.Įvery level includes access to the Trading Room, all the premium content in the modular video academy, daily live trading sessions, trade sentiment analysis, weekly hot pick analysis, real time global news stream, live interactive workshops and access to pro trader tools. You can expect the free courses to include both forex and stocks education – from a basic introduction through to charts, technical analysis, indicators, risk management and psychology.Īlongside the free courses, there is premium content that comes with membership of the Trading Room. There are more than 50 free trading lessons, designed by globally recognised mentors, and when you complete them, you will receive a certificate. Providing a trading education that is designed to take you from the basics through to the advanced strategy, How to Trade has a wealth of world-class educational resources. If you join now you will be able to take advantage of the current flash sale - the system is reduced from $297 to only $97. The 1000pip Climber system is a great option for traders who want a high performance robot that is simple to install and use. Another key advantage of this system is the 24/7 support and free updates for life. The interface has been kept clear and simple so that even beginners would find it easy to use. Unlike many other robots all complexity is kept internal and there are almost no settings for the user to adjust. The robot is particularly well suited to inexperienced traders because the robot is very easy to install and use. This provides an added layer of confidence in the quality of the algorithm. The historical test performance has been outstanding and most importantly the performance has been independently verified by MyFXBook. ![]() What makes this robot stand out is the impressive combination of an extremely advanced trading algorithm in a very easy to use package. MArketing66 may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers.The 1000pip Climber forex system is one of the best FX robots available. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website. It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of MArketing66 and/or the data provider. MArketing66 and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Marketing66 would like to remind you that the data contained in this website is not necessarily real-time nor accurate. Before deciding to trade in financial instruments or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed. Trading on margin increases the financial risks. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors.
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![]() ![]() It’s great that you can pick up different parts as collectible items in each mission, but it’s a slight disappointment that you can’t alter your loadout just anywhere. I'm used to it, coming straight off of DOOM Eternal which uses that style of shooting, but it's still potentially disorienting for those transitioning from modern military shooters like COD. While ADS for non-scoped weapons is accessible to a limited extent via a cheat code that can only be unlocked later in the campaign, Trepang’s slick movement and slow-mo features make it easy to close the gap between opponents, effectively balancing combat around the use of crosshairs for aim akin to old-school shooters like DOOM and Halo. I'm ambivalent about Trepang2's lack of a default aim down sights feature for weapons with iron sights, veering toward Counter-Strike rather than Call of Duty in its military shooting inspirations, but it still works just fine without it. Powersliding through ammo, health, and armor pickups and occasionally popping up to wreak carnage on the next group of enemies I encounter feels great. ![]() Adding to the frenzy of Trepang2's combat is a melee button that feels great to use, and it lets you beat your enemies down or unleash a Spartan Kick once you've closed the gap, making it easy and often hilariously fun to direct the flow of the carnage in slow-mo.ĭipping into that slow-mo Focus ability almost always let me pick off a few pesky foes before my meter ran out, and since diving around cost nothing, Trepang2 is at its best when you stay on the move while your Focus meter recovers in the background. The reload animation when dual-wielding two unfolded shotguns will never cease to make me laugh, and running into the fray with two weapons of any variety feels badass no matter how successful you are at landing kill shots. Likewise, it's slightly disappointing you can only dual-wield identical weapons, so there's no mixing and matching a shotgun with an SMG.īut it pays off with a gratifying spectacle when you decimate a crowd of armored bad guys in slow motion, brandishing two shotguns or assault rifles like toys. Dual-wielding adds an extra dimension to gunplay in that you can become lethal at close range when dual-wielding any weapon, though you'll struggle to pick off enemies from afar. Pistols, SMGs, shotguns, and assault rifles can be dual-wielded once you find the hilariously titled "Dual-Wield Serum", and that's fortunately unlocked about halfway through the campaign. ![]() Its run-of-the-mill arsenal of weapons may bore at first glance, but they handle well with a mouse and keyboard, and I enjoyed using them just as much with my handy Xbox One controller. This all speaks to its excellent open-ended combat across its six primary and six side missions, wherein its eight highly customizable weapons gave me just as much leeway to simply dive into the action and kill everyone in sight on my own terms. Trepang2 often lets you shoot out lights to pass under the cover of darkness or set traps for a good old ghillied-up time. And I didn’t miss it, because great level design is far more important to stealth than a lazy invisibility button. I’m not much of a stealth player, and it always seemed like the cooldown timer for my Cloak ability was a bit too long for my tastes anyway, so I generally forgot about it. It’s especially important to remain versatile since there are often so many enemies on screen at once – maybe as many as 20 or 30 – and they will relentlessly group up on you, flank you, and appear to communicate your position to one another, making cover basically useless in the heat of battle unless you’re able to stay hidden. Mixed with a button that lets you dive into a crouching position whenever you want, these abilities give you superhuman prowess in most situations, but not so much that Trepang2 ever made me feel overpowered – at least once I turned the difficulty up a notch or two. Halfway through the first level you’re already introduced to Subject 106’s nifty Cloak and time-slowing Focus abilities. The cinematography pales in comparison to other period pieces of note such as Netflix’s Ratched. But I think this was a story that needed to be told, if anything to encourage viewers to research the real Radium Girls’ tale for themselves. While the historical premise itself carries the story somewhat, it gets bogged down by lackluster characters. The writing leaves something to be desired. In fact, I’d be interested to see a spin-off film that centers on her. Heyward proffered a memorable turn as Etta. Yet Minifie injects Doris with an infectious tenacity that shines through the brief time she’s on screen. She can no longer walk without assistance. Doris is in the late stages of radium poisoning. Minifie only had a supporting role, but it was a memorable one. Without the gripping story, I don’t think I’d feel much for the other characters. Bessie is really the only character who evolves in Radium Girls. Quinn’s character was far more intriguing, although she had less screen time and less development. But her performance here isn’t anything to write home about. King is always a dependable performer who steps up to the plate. Performance-wise, I wasn’t particularly dazzled. Radium Girls‘ lessons are clear and ever present throughout its 102-minute run. The privileged, like Bessie, are blissfully unaware of the struggles minorities (like Etta) face. The lesson? Corporate greed will always take precedence over “the little guy.” History is doomed to repeat itself, as it already has. ![]() Strangely enough, this film was initially released at the Tribeca Film Festival in 2018, two years prior to the Coronavirus pandemic sweeping the globe. The United States’ blatant negligence regarding virus containment is quite similar to American Radium’s handling of the poison cases. The Radium Girls’ fight to ban radium usage and seek justice is akin to our own battle against COVID-19. We see 1920s protestors taking to the streets, flaunting signage that condemns police brutality and uplifting a woman’s right to vote with impunity. Black and white footage of Etta’s filming is spliced between scenes throughout the film. She meets Etta ( Susan Heyward), a Black filmmaker who’s keen on pulling back the veil regarding injustice. Along the way, Bessie learns about social injustice plaguing the world over through her boyfriend’s advocacy group. ![]() Two other women, Paula ( Olivia Macklin) and Doris ( Colby Minifie), join the fray in bringing American Radium to justice. Now, her other sister, Josephine ( Abby Quinn), has fallen ill.īessie and Josephine decide that enough is enough. Joey Kingstars as Bessie, a young woman who’s lost her older sister to radium poisoning that American Radium, the company she works for, claimed was merely “syphilis.” She noticed that an awful lot of deaths at the hands of American Radium were being categorized as syphilis. Additionally, it led to better workers compensation and strict radiation regulations for industrial settings. Their historic victory paved the way for radium to be banned from watches and, well, just about everything. The company was forced to pay any financial damages incurred on behalf of these women for as long as they lived. ![]() A handful of women decided to take a corporation called Radium Dial Company to task. Unfortunately, several died from said radium poisoning. Of course, at the time, everyone assumed radium was good for you. Why? They were encouraged to lick the brushes they were using to paint these watch dials. Some of the women who worked at these factories fell violently ill due to radium poisoning. Nowadays, hearing the word “radium” is enough to instill a sense of pervasive fear. Radium was “liquid sunshine.” It could cure cancer! It’ll bring an ethereal glow to your cheeks! The real-life event involved a slew of factory girls in the 1920s who painted watch dials. I had no idea that these “Radium Girls,” as they were dubbed by the press at the time, existed. However, I didn’t know the full extent of the story explored therein. Prior to watching Radium Girls, I was aware that it was based on true events. DISCLAIMER: Spoilers lie ahead for Juno Films’ Radium Girls. ![]() The challenge is that the words are hidden. The grid itself consists of a pattern of horizontal and vertical intersecting words. Use the provided clues to identify words that fit in the puzzle grid. Reprinted by Permission."ĭo you know a special needs student, such as a child or adult with autism or severe ADHD, who might enjoy solving puzzles on paper? Then check out my collection of Special Needs Word Search puzzles. In your publication, simply include the following copyright statement next to each puzzle: "©. without restriction.Īre you the publisher of a newsletter, bulletin, newspaper, or magazine? Include a crossword puzzle, word search puzzle, or sudoku puzzle in each issue. You can email the crossword PDF file to anyone, or put it on your blog, website, etc. Sharing These Puzzlesīasically you can do whatever you like with the crosswords except sell them. For example, you might find the Literary Terms crossword to be tough if you aren't familiar with the specialized lingo used by writers. Note: Having said that, some of these crossword puzzles are more challenging than others due to the particular subject matter. But there is nothing in these easy printable crossword puzzles that I would consider crazy-difficult. And it's never satisfying to just leave a puzzle half-finished.īecause I want this crossword puzzle collection to have wide appeal, I have minimized the difficulty level. On the other hand, many people aren't thrilled by the prospect of tackling a puzzle that requires them to know lots of obscure facts. However, most of the puzzles in it are pretty tough. It's a great puzzle book, and I recommend it. I've owned a copy of the hard-back crossword puzzle book, "The New York Times Little Black (and White) Book of Crosswords" for years and occasionally challenge myself with one of the harder puzzles. Some crosswords will also indicate the number of words in a given answer, should there be more than one.I am not against hard crossword puzzles. At the end of the clue the total number of letters is sometimes given, depending on the style of puzzle and country of publication. The clues are then referred to by these numbers and a direction, for example, "4-Across" or "20-Down". Squares in which answers begin are usually numbered. The shaded squares are used to separate the words or phrases. In languages that are written left-to-right, the answer words and phrases are placed in the grid from left to right and from top to bottom. The goal is to fill the white squares with letters, forming words or phrases, by solving clues which lead to the answers. And just for those who don't know, a A crossword is a word puzzle that normally takes the form of a square or a rectangular grid of white and shaded squares. These worksheets are fun, colorful, and educational. That's because our crossword puzzles quiz students on important vocabulary words. ![]() Best of all, they'll still be learning while they do them. This will give them a gentle break, allowing them to work together and relax. ![]() Pass these worksheets out to students between more difficult lessons. ![]() Crossword Puzzle Worksheets Terms of Use Not only are crossword Puzzles fun to complete, but they also provide for a great teaching opportunity. ![]() NuCore FlooringĪbout the Brand: Inexpensive and aesthetically pleasing, NuCore vinyl plank flooring is an exclusive product manufactured and sold by Floor & Decor. Shop for more Mohawk vinyl plank flooring at: ![]() Get the Mohawk Hazelnut Oak Plank Vinyl at The Home Depot for $1.09 per square foot Mohawk Hazelnut Oak Plank Vinyl: Made for DIYers on a budget, the Mohawk Hazelnut Oak Plank vinyl plank sheet flooring utilizes a top coat of urethane to help protect against stains, scuffs, and scratches.The lower- priced Mohawk products may lack some of the premium features offered by competitors, but the average users (and their wallets) can appreciate the reliable design and the inexpensive price. Mohawk still prides itself on producing affordable flooring options with reliable quality. Since its reformation in 1988, Mohawk has grown significantly, acquiring more than 34 companies. The company underwent several more changes until the carpet business was dropped from the parent company (named Mohasco at the time) and reformed into Mohawk Industries. ![]() However, that name didn’t exactly roll off the tongue, so when the company merged with another carpet mill in 1920, it was changed to the Mohawk Carpet Mills. In 1878 It moved to Amsterdam, New York, but it didn’t become an official company until 1902 as the Shettleworth Brothers Company. Mohawk started out in 1875 as a simple carpet mill that was operated by a father and his four sons. Shop for more COREtec vinyl plank flooring at:Ībout the Brand: The Mohawk brand of vinyl plank flooring is one of the most affordable options available to DIYers looking to update their homes without emptying their wallets. Get the COREtec Plus 5″ Waterproof Vinyl Planks at Flooring Inc for $5.49 per square foot
(I am using CMake 2.6 and boost 1.40.0) boost. Am I going about this the right way, and if so where should I point CMake to find these libraries. Target_link_libraries(example /opt/boost/lib/libboost_system. Using, Building, and Configuring Boost.Asio Supported Platforms The following platform and compiler combinations are regularly tested: Linux using g 4.6 or later Linux using clang 3.4 or later FreeBSD using g 9 or later macOS using Xcode 10 or later Win32 using Visual C 11. findpackage (Boost 1.40.0 REQUIRED COMPONENTS asio) CMake then asks for BoostASIOLIBRARYDEBUG and BoostASIOLIBRARYRELEASE. ![]() Target_link_libraries(example boost_system)Īnd the alternative is to explicitly list the library in target_link_libraries rather than the target: include_directories(/opt/boost/include) IMPORTED_LOCATION /opt/boost/lib/libboost_system.a It is a general solution to managing dependencies in a light way in. Try CPM.cmake Instead This repo is no longer maintained, please try CPM.cmake instead. Set_property(TARGET boost_system PROPERTY ASIO-CMake provides handy cmake pacakage wrapper for using ASIO. The first approach creates an imported CMake target: add_library(boost_system STATIC IMPORTED) If you do not have a proper Boost installation, then there are two approaches to statically link against the libraries. The easiest way is to use FindBoost.cmake provided in a CMake installation: set(BOOST_ROOT /opt/boost) In my environment, I have installed Boost to /opt/boost. DRIVER=Microsoft Access Driver (*.mdb, *.accdb) UID=admin UserCommitSync=Yes Threads=3 SafeTransactions=0 PageTimeout=5 MaxScanRows=8 MaxBufferSize=2048 FIL=MS Access DriverId=25 DefaultDir=C:\ExampleDir DBQ=C:\ExampleDir\app\pp.If I understand the actual question, it is fundamentally asking how to statically link against 3rd party libraries in CMake. User DSN lists driver for accdb, but this is no DSN.Īttached is the dsn file my program is using: When I am selecting the respective user DSN for configuration, the following error message is popping up: Error Message when attempting to configure an existing, previously working DSN The azmq library provides Boost Asio style bindings for ZeroMQ. However, a lot of software is created and maintained in C/C and there is no out-of-the-box package manager for that. This C binding for 0mq/zmq is a high-level library that hides most of the c-style. Only only drivers for mdb files are listed, no 64 bit accdb drivers. 1 Photo by Claudio Schwarz on Unsplash Introduction Today, modern languages (e.g., Go) often provide integrated package management for pulling all dependencies of a library. Use this module by invoking findpackage () with the form: findpackage (Boost version EXACT Minimum or EXACT version e.g. I attach one image, which currently is the similar for all three type of DSNs. In order to build the examples, you need to install CMake, which is one of the most popular cross-platform build tools for C programs. This module finds headers and requested component libraries OR a CMake package configuration file provided by a Boost CMake build. D:mingw64bing .exe -fdiagnostics-coloralways -g -I D:boostboost1820 'D:Developmentsimplefolder. However i am getting a bunch of linker errors in the terminal : Starting build. It seemed that temporarily I could use an existing ile dsn, but no system or user dsn. So i am trying to compile the absolute basic ASIO tutorial code as given here. I am using MS Access runtime 16 and I installed it to have access to ODB6 64 bit drivers, which were not showing in the ODBC dialog. When I started using my program, there were some driver related problems with respect to my application connecting to an MS Access database. So I installed the newest CMake ( cmake version 3.19. ![]() For my case, I am going to use Boost.Asio. I want to include boost::asio in my c Project under Ubuntu 18.04 with a cmake file. I had to reinstall Windows 10 Pro and this went well. You can refer to this link to install latest CMake for your Raspberry Pi. cquillen Asks: Using boost.asio in CMake I am relatively new to CMake, and Im trying use the boost asio library in my project. With 1.13 and later, the standalone mode is enabled by default if ASIOENABLEBOOST is defined and C 11 is detected. Before 1.13, ASIOSTANDALONE has to be added to the compile definitions to disable inclusion of boost headers. Michaelinscarbororough Asks: MS Access ODBC 64 drivers Asio does not detect by itself whether it's being used with boost or in standalone mode. ![]() It's hilarious trash, shoot it right into my veins! And at rare times it can be legit funny and have a certain charm to its cast, especially with the main protag being a ridiculous anxiety-driven loser. Janky art aside, the chapters are often utter chaos of things just happening and characters obsessing over the most meaningless things, which makes for amazing riffing material (just remember that silly toilet scene!). Maybe there still is some massive demand for hitman/spy/assassin action-comedy that even the vastly superior Yozakura Family and Sakamoto Days plus SPYxFAMILY on Jump+ can't satisfy on their own?Īnd of course Nü Sexorcist Nue's Exorcist doing well (if the rank keeps up) would also be a surprise, but I can at least ironically enjoy that mess, lol. A tired concept ("ANOTHER hitman/spy/assassin series, but this time in highschool"!!), surprisingly lifeless and lackluster art for a veteran, paired with barely motivated characters and mean-spirited boomer jokes which ig somehow is popular with current readers, apparently. Meanwhile, Kill Blue might be some of the most unlikeable garbage I have seen in the magazine in years, outside of the various gag-flops. I assume it's too technical and sincerely passionate for teenagers but that usually shouldn't be a dealbreaker. Tenmaku Cinema is an incredibly well executed series about filmmaking with a great cast, fantastic art and a lot of passion for the art plus a popular vetaran duo and it somehow doesn't catch on, apparently. On top of this, we must also consider that this isn’t even based on scum villain, and is ANOTHER romantic classic historical drama, where we have a cute little FL falling in love with an OP QX.Īnyways, just a reminder this is all my 3am speculation born from overthinking, NONE OF THIS IS FOR SURE, and I could very well be completely wrong.New series' placement in recent ToCs are pretty baffling to me. For example, LBH could be considered both the male lead, the villain, and maybe even the master (if you consider the later parts of the novel) and SQQ could be considered the villain, the MC, and the master (during LBH’s disciple hood) Due to the nature of the plot, the characters have many ambiguous roles. It is difficult to assume the roles WY and QX might play if the novel is in fact based on scum villain. In that case, the ‘male lead’ aka LBH, should be played by Qin Xian, and ‘SQQ’ should be played by Wang Yi (lol a transmigrator playing a transmigrator) but this logic is incongruent with the statement that Wang Yi won’t be a master. Since all of the novels Wang Yi goes through seem to be teen girl novels, the plot shouldn’t follow PIDW logic. However, this doesn’t line up with a couple aspects of their character and roles respectively. However, according to comment, it looks like this time around Wang Yi “won’t be a master” Now, assuming this will be a reference to Scum Villain, this means Wang Yi will play the role of LBH, and Qin Xian plays the role of SQQ. ![]() ![]() ![]() Now idk if any of y’all know what scum villain is, but if we look at Wang Yi’s character design in that panel, he has Luo Binghe’s heavenly demon mark on his forehead, as well as the green Qingjing Peak robes LBH wore during his discipleship (although the hair accessory does look like something SQQ would wear maybe his character is closer to shizun) If we refer to that one panel with multiple forms of Wang Yi (refer to chapter 17) it looks like the illustrations line up with Wang Yi’s role in each plot line. Ok guys so I read the comment by (below) and according to their comment it looks like the next world will be a xianxia! >v<</p> ![]() Back in August, the United States Department of Energy and Cray announced plans for a third United States exascale supercomputer, El Capitan. Boot the computer you want to install El Capitan on with 'alt' held and select your USB drive. Then, choose the disk you want to install the El Capitan installer on. Scheduled to be installed in Lawrence Livermore National Laboratory (LLNL) in early 2023, the system is intended primarily (but not exclusively) for use by the National Nuclear Security Administration (NNSA), who uses supercomputers in their ongoing nuclear weapons modeling. For details about your Mac model, click the Apple icon at the top left of your screen, choose About This Mac, then choose More Info. Make sure you have Install OS X El Capitan.app in your Application Folder Select 'On an external drive' on the main MCPF window. At the time the system was announced, The DOE and LLNL confirmed that they would be buying a Shasta system from Cray (now part of HPE), however the announcement at the time didn’t go into any detail about what hardware would actually be filling one of Cray’s very flexible supercomputers.īut as of today, the wait is over. This afternoon the DOE and HPE are announcing the architectural details of the supercomputer, revealing that AMD will be providing both the CPUs and accelerators (GPUs), as well as revising the performance estimate for the supercomputer. Perian For El Capitan Os Perian For El Capitan 10. Keep visiting themacgo the world of dmgs. This link is resume able within 24 hours. 1981) granitic plutons that constitute the bulk of the intrusive suite of Yosemite Valley (Bateman 1992) within the Sierra Nevada batholith of east-central California. We are here to provide to clean and fast download for Mac OS X El Capitan 10.11 dmg. The El Capitan Granite is a large group (>300 km 2) of mid-Cretaceous (103 Ma Stern et al. However thanks to some late configuration changes, the DOE now expects the system to reach 2 exaflops once it’s fully installed, which would cement its place at the top of the US’s supercomputer inventory.Īlready expected to be the fastest of the US’s exascale systems, El Capitan was originally commissioned as a 1.5 exaflop system seven months ago. Click on the button below to start downloading Mac OS X El Capitan 10.11.1 for mac OS X. Pavtube Studio updated its Mac products to meet the trend to prevent Pavtube users from the softwares incompatibility with El Capitan issue. However thanks to some late configuration changes, the DOE now expects the system to reach 2 exaflops once it’s fully installed, which would cement its place at the top of the US’s supercomputer inventory. When they are enjoying the benefits OS X El Capitan brought, many of them are suffering the softwares incompatibility issue on Mac OS X El Capitan, such as Blu-ray Ripper and DVD Ripper. Overall, El Capitan is the second ( and apparently final) system being built as part of the US DOE’s CORAL-2 program for supercomputers. Overall, El Capitan is the second ( and apparently final) system being built as part of the US DOE’s CORAL-2 program for supercomputers. ![]() For little ones who aren’t yet at the point of cutting up their own ‘cado, most supermarkets sell avocado spreads that work just as well. Avocado toast Image via Glowing Plants/InstagramĮven if they’re not millennials, kids can still enjoy avocado toast, like this “bomb” rendition from Glowing Plants. For kids who are too young to make oatmeal on their own, you can either make overnight oats that you leave in the fridge, or make slow cooker oats the night before and leave in the Crock-Pot. Oatmeal with banana Image via Shelley Cronkhite Huber/InstagramĪnother favorite of Thompson’s? Oatmeal topped with a banana, such as this one from Shelley Cronkhite Huber. Cut up chunks of fruit and freeze in individual bags so kids just need to add the milk of their choice and, for added protein, a dollop of nut butter. If the kiddos are experienced enough to use the blender, breakfast smoothies, like this one from Aimz High Fitness, are a great option that can be half-prepped the night before. Breakfast smoothie Image via Aimz High Fitness/Instagram Or they can get creative and try coming up with their own variations! 4. They just need a few ingredients to get started: 1) whole wheat toast, 2) cream cheese, peanut butter, nutella and/or hummus and 3) some blueberries and/or cut-up bananas and strawberries. Speaking of toast … creative kids will love making animal face toast in the morning. ![]() Whether they want to jazz it up with fruit and seeds or be an absolute purist, nut butter on whole grain bread or toast, like this beauty from Lenna Omrani, is always a great breakfast kids can make. Nut butter on whole-grain bread Image via Lenna Omrani/Instagram Easy - and fun - for any kiddo to fix themselves! 2. One of Thompson’s favorite breakfasts is a yogurt parfait, which is simply yogurt with layers of whole-grain cereal and fruit. ![]() So, why not have the kids take care of breakfast while you take care of everything else?įrom super-simple twists on plain ol’ toast to leftover pizza (yes, really), here are 20 easy breakfast ideas for kids to make. Oversleeping, lost homework, sibling squabbles - the factors that contribute to hastily eaten cereal are endless. While parents and caregivers know the importance of sending kids to school after a healthy breakfast, life often gets in the way. Sounds easy enough, right? For families pressed for time in the morning, not necessarily. Studies have shown that a healthy breakfast improves memory and concentration and is also associated with less tardiness and fewer behavior problems.”Īccording to Thompson, the ideal breakfast should include a hearty source of carbohydrates ( with fiber), as well as protein, which “minimizes hunger in the long break before lunchtime.” “It’s a key component of the morning that helps kids achieve academic goals, as well as maintain healthy weight. “Including a healthy breakfast before the school day starts is just as important as getting enough sleep,” says Jenifer Thompson, an advanced-practice dietician with expertise in pediatric nutrition therapy at Johns Hopkins. And when you’re a kiddo who’s about to spend six hours in school, it’s doubly important to heed this age-old message. If you’ve heard it once, you’ve heard it 1,000 times: Breakfast is the most important meal of the day. ![]() Increased release of cortisol and ACTH have also been observed in patients with mood disorder. ![]() These, in turn, increase sensitization and vulnerability to mood disorders. High levels of cortisol would induce cell dysfunction or reorganization of dendrites in neurons in the long run, ultimately leading to significant neuroanatomical changes. Cortisol and ACTH are important biological indicators of a dysfunctional HPA axis and have been included as routine clinical test items to evaluate the status of the axis. The activity of the hypothalamic-pituitary-adrenal (HPA) axis can be modulated by gonadal hormones. Presently, the relationship between gonadal hormones and mood episodes is unclear, and some studies have suggested that it may be related to mood episodes. Testosterone has been found to participate in the pathological process of BD and has anxiolytic and antidepressant effects in humans and animals, which are known to benefit negative emotions. Progestogens have significant, though indirect, effects by converting into neuroactive molecules, such as estrogens and testosterone. Estradiol is involved in a wide range of brain functions, including neurodevelopment, neuroplasticity, and anti-inflammatory effects, which have implications for emotions. Women with BD are more vulnerable to suffering from depression and an increased risk of affective dysregulation during periods of hormonal fluctuation. The widespread effects of gonadal hormones in the brain and pathophysiology of affective disorders, have become increasingly evident in recent decades. Therefore, to enrich the existing evidence, more and broader potential biomarkers need to be explored. Circulating blood-derived markers related to pathophysiologic processes of BD have been reported to differ among mood episodes, but none have been translated into clinical tests for traits or episodes of BD. ![]() Several studies have linked BD with sex hormone fluctuations, stress and inflammatory response. However, the etiology of BD is complex and not fully understood. The disorder results in significant functional impairment and high mortality, imposing a heavy social and economic burden on individuals, families, and countries at large. Globally, over 1% of the population is affected by BD. Our findings not only provide mood episode-related biological markers, but also better support for targeted intervention in BD treatments.īipolar disorder (BD) is a chronic recurrent disorder characterized by mood swings, involving episodes of mania, hypomania, and alternating depression. The biological signatures of mood episodes in BD patients may be sex- and age-specific. While both hormone and inflammatory change is independently associated with mood episodes, we found that the combination of sex hormones, stress hormones and CRP could be more effective to differentiate the manic and depressive episode. Furthermore, we found a sex- and age-specific impact of combined biomarkers in mood episodes in male BD patients aged ≥ 45 years (AUC = 0.70, 95% CI, 0.634–0.747), not in females. The episode-specific changes of testosterone, ACTH, and CRP levels remained between the two groups ( P < 0.001) after correction for the confounding factors including age, sex, BMI, occupation, marital status, tobacco use, alcohol consumption, psychotic symptoms, and age at onset. In overall comparison between mood episodes, the BD patients expressed higher levels of testosterone, estradiol, progesterone, and CRP ( P < 0.001) and lower adrenocorticotropic hormone (ACTH) level ( P < 0.001) during manic episode. A receiver operating characteristic (ROC) curve was used to analyze the discriminatory potential of the biomarkers for mood episodes. A panel of blood tests were performed for levels of sex hormones (serum levels of testosterone, estradiol, and progesterone), stress hormones (adrenocorticotropic hormone and cortisol), and an inflammation marker (C-reactive protein, CRP). All patients were in acute state of mood episodes and need hospitalization. MethodsĪ total of 8332 BD patients (n = 2679 depressive episode n = 5653 manic episode) were included. In this study, we investigated the changes of various hormones and inflammatory markers across distinct mood episodes of BD in a large clinical study to provide mood episode-specific peripheral biomarkers for BD. While hormones imbalance plays important role in the mood swings, it is unknown whether peripheral hormones profiles could differentiate the manic and depressive mood episodes in BD. Bipolar disorder (BD) is characterized by intensive mood fluctuations. |
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